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分子生物學
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查看說明書Recombinant S100 Calcium Binding Protein B (S100B)
Cat#:TP03839應用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | S100B Recombinant Rabbit mAb |
| Cat No.: | RMA01005 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC, ICC/IF, IP |
| Recommended Dilution: | WB, IHC, ICC/IF, IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human S100B |
| Calculated Molecular Weight: | 11 kDa |
| Observed Molecular Weight: | 11 kDa |
| GenBank Accession Number: | P04271 |
| Gene ID (NCBI): | 6285 |
| Synonyms: | NEF; S100; S100-B; S100beta |
| Background: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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